Sponsor Deadline for Letters of Intent (requested but not required): 30 days in advance of the full proposal deadline

FAS/SEAS/OSP Deadline: 5 business days prior to submission

Sponsor Deadlines for Full Proposals: October 13, 2022; October 13, 2023

Award Information: Application budgets are limited to $300,000 in direct costs excluding consortium F&A in any year for the UG3 phase (not to exceed 3 years). Applications should rarely exceed $750,000 in direct costs excluding consortium F&A in any year for the UH3 phase (not to exceed 4 years). The total combined duration of the UG3 and UH3 must not exceed 5 years. The BRAIN Initiative intends to commit $18M to fund an estimated up to 4 awards each fiscal year.

This FOA solicits applications for team-centric development and validation of innovative non-invasive imaging technologies that could have a transformative impact on the study of brain function/connectivity. Applications are expected to turn a novel concept into a functional prototype using this phased grant mechanism. The feasibility should be established by the end of its first phase and serve as a foundation for the transition to its second phase. Fully developing the technology into a functional prototype and validating it by in-vivo animal or human function/connectivity imaging are anticipated in the second phase. The research plan should provide a realistic timeline and tangible milestones to support the proposed development effort. Awards will be integrated into the BRAIN Non-Invasive Imaging Consortium, as a coordinated network on brain function/connectivity imaging.

Applicants are strongly encouraged to consult with NIH program staff when planning an application, preferably well before the Letter of Intent due date.